ABSTRACT
Background: Dyslipidemia is one of the modifiable risk factors of coronary heart disease
Objective: to determine the pattern of dyslipidemia in young patients with dyslipidemia
Methodology: a total of 120 patients, 20 to 40 years of age of either gender with acute Myocardial Infarction were included in this cross sectional study, from 1[st] January to 30[th] August 2015. Patients with history of ischemic heart disease, chronic renal failure, hypothyroidism, diabetes mellitus, and were hypertensive and on statin therapy were excluded. Venous blood sample was taken and sent to laboratory for analysis of following parameter serum total cholesterol level, serum triglycerides level, low density lipoprotein [LDL] and high density lipoprotein [HDL]. This data entered was and analyzed and using SPSS version 16
Results: mean age was 34.13 +/- 4.57 years. Out of these 120 patients, 80.83% were males and 19.17% were females with male to female ratio of 4.22:1. Dyslipidemia was present in 73 [60.83%] patients while 47 [39.17%] has shown normal lipid profile. Among total patients hypertriglyceridemia was present [45%] followed by hypercholesterolemia [36.67%], raised LDL [25.83%] and low HDL [10.83%]
Conclusion: this study concluded that there is a high frequency of dyslipidemia in young patients presenting with acute myocardial infarction
ABSTRACT
Background: Acute myocardial infarction [AMI] is one of the most deadly disease of the cardiovascular origen. Older patients are more likely to have a "silent" or unrecognized AMI and to develop heart failure, atrial fibrillation, cardiac rupture, and shock, all of which are associated with increased mortality and a poor prognosis
Objective: To determine the frequency of in-hospital outcome of octogenarians with acute ST segment elevation Myocardial infarction
Methodology: This cross sectional study was conducted at department of Cardiology, Chaudhary Pervaiz Elahi Institute of Cardiology, Multan from 25[th] October 2014 to 25[th] April 2015. 140 octogenarian patients of acute myocardial infarction were included in the study and clinically followed during hospital stay. The outcome variables included were mortatilty, cardiogenic shock, post MI angina and arrhythemia. SPSS version 20 was used for data entry and analysis
Results: Mortality was observed in 12 [8.6%] of our study cases, cardiogenic shock was noted in 47 [33.6%], post MI angina was noted in 45 [32.1%] and arrhythmia was noted in 53 [37.9%] of our study subjects
Conclusion: High frequencies of arrhythmia, cardiogenic shock and post MI angina have been noted in elderly patients in our study
Subject(s)
Humans , Male , Female , Aged, 80 and over , Aged, 80 and over , Hospitals , Patient Outcome Assessment , Cross-Sectional StudiesABSTRACT
Background: Congenital anomalous origins of the coronary arteries are a rare but well-described cause of myocardial ischemia and sudden death
Objective: To determine the frequency of coronary artery anomalies in adult patients undergoing coronary angiography for ischemic heart disease
Methodology: A total of 493 consecutive patients with diagnosed Ishemic Heart Disease [IHD] visiting Department of Cardiac Catheterization, Ch. Pervaiz Elahi Institute of Cardiology, Multan were included in this cross sectional study from 15[th] June to 15[th] December 2014. Diagnostic coronary angiography was carried out. The outcome variable i.e. coronary anomalies as defined in operational definition were noted on the performa
Results: There were 493 patients. Males were 293 [59.4%] while females were 200 [40.6%]. Mean age of the patients was 54.45 +/- 13.02 years ranging in age from 18 to 70 years. Coronary artery anomaly was identified in 8 [1.6%]. Separate left anterior descending and left circumflex artery was observed in 2 [0.4%], Left circumflex artery arising from right coronary sinus was observed in 1 [0.2%], Right coronary artery arising from left coronary sinus was observed in 2 [0.4%], left coronary artery arising from right coronary sinus was observed in 1[0.2%] while myocardial bridging was observed in 3 [0.6%]. One of the patients with myocardial bridging also has left coronary artery arising from right sinus
Conclusion: Myocardial bridges were the most frequently encountered problem followed by separate origins of LAD and left circumflex and then right coronary artery arising from the left coronary
ABSTRACT
Background: Periprocedural myocardial infarction has been a matter of concern for cardiac interventionists and role of high dose statins is being widely studied now a days
Objective: To compare the frequency of peri-procedural non-Q-wave myocardial infarction between patients who received and not received high dose atorvastatin before percutaneous coronary intervention [PCI]
Material and methods:- This randomized controlled study was carried out from 1[st] February, to 31[st] August, 2010 at Ch. Pervaiz Elahi Institute of Cardiology, Multan. A total of 222 patients with unstable angina on chronic statin therapy undergoing PCI were randomized to atorvastatin high dose bolus group I [80 mg,12 hours before intervention, n=l 11] or group II no atorvastatin [n=l 11]
Results: Mean age in group I, was 53 years and in group II, was 55 years. It was noted that majority were female [88%] in group I, whereas Male [92%] in group II. 33% in group I and 37% in group II were diabetics. Similarly hypertension, smoking prevalence was comparable in both groups. Periprocedural MI occurred in 6 [5.4%] patients in group-I and 17 [15.3%] patients in group-II
Conclusion: It is concluded from the study that preloading with high dose [80 mg] atorvastatin bolus before PCI reduces peri-procedural MI in patients on chronic statin therapy undergoing PCI